Tir (AA 252-362) 抗体 (Biotin)
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北京 101111
Quick Overview for Tir (AA 252-362) 抗体 (Biotin) (ABIN7141627)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 252-362
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原理
- tir Antibody, Biotin conjugated
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交叉反应
- E. coli
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Tir
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背景
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Background: Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).
Aliases: tir antibody, espE antibody, ECSP_4676 antibody, Translocated intimin receptor Tir antibody, Secreted effector protein Tir antibody
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UniProt
- C6UYL8
抗原
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