P4HB 抗体 (AA 20-509) (HRP)
Quick Overview for P4HB 抗体 (AA 20-509) (HRP) (ABIN7141116)
抗原
See all P4HB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-509
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交叉反应
- Chinese Hamster
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Cricetulus griseus Protein disulfide-isomerase protein (20-509AA)
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亚型
- IgG
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anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibody
P4HB 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibodyP4HB 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) antibodyP4HB 适用: 人 WB, IF, ICC, IHC (p), IEM 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (N-Term) antibodyP4HB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 329-508) antibodyP4HB 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 1-508) antibodyP4HB 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibodyP4HB 适用: 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (C-Term) antibodyP4HB 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 兔, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 499-509) antibodyP4HB 适用: 人, 小鼠, 大鼠, Hamster, Cow, 犬, 猴, 豚鼠, Pig, 绵羊, 兔, 非洲爪蟾, 小鸡 WB, IHC, ICC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Prolyl 4-Hydroxylase, beta Polypeptide (P4HB) (AA 409-509) antibody (HRP)P4HB 适用: 大鼠 WB, IHC, IP, IF, ICC 宿主: 兔 Polyclonal HRP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
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别名
- P4HB
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背景
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Background: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9, the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration.
Aliases: P4HB antibody, PDIA1Protein disulfide-isomerase antibody, PDI antibody, EC 5.3.4.1 antibody, Prolyl 4-hydroxylase subunit beta antibody, p58 antibody
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UniProt
- Q8R4U2
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途径
- Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
抗原
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