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RABAC1 抗体 (AA 16-299) (Biotin)

This anti-RABAC1 antibody is a Rabbit Polyclonal antibody detecting RABAC1 in ELISA. Suitable for Candida albicans.
产品编号 ABIN7140909
发货至: 中国

Quick Overview for RABAC1 抗体 (AA 16-299) (Biotin) (ABIN7140909)

抗原

See all RABAC1 抗体
RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))

适用

  • 5
  • 4
  • 1
  • 1
Candida albicans

宿主

  • 8
  • 1

克隆类型

  • 8
  • 1
多克隆

标记

  • 7
  • 1
  • 1
This RABAC1 antibody is conjugated to Biotin

应用范围

  • 7
  • 7
  • 2
ELISA
  • 抗原表位

    • 4
    • 1
    • 1
    • 1
    AA 16-299

    交叉反应

    Candida albicans

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RABAC1 (Rab Acceptor 1 (Prenylated) (RABAC1))

    别名

    PRA1

    背景

    Background: Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.

    Aliases: PRA1 antibody, FBP1 antibody, CAALFM_C406980WA antibody, CaO19.10623 antibody, CaO19.3111 antibody, pH -regulated antigen PRA1 antibody, 58 kDa fibrinogen-binding mannoprotein antibody

    UniProt

    P87020

    途径

    Chromatin Binding
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