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KRT17 抗体 (AA 1-441) (HRP)

This anti-KRT17 antibody is a 兔 多克隆 antibody detecting KRT17 in ELISA. Suitable for Cow.
产品编号 ABIN7140841
发货至: 中国

Quick Overview for KRT17 抗体 (AA 1-441) (HRP) (ABIN7140841)

抗原

See all KRT17 抗体
KRT17 (Keratin 17 (KRT17))

适用

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Cow

宿主

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克隆类型

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多克隆

标记

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This KRT17 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 1-441

    交叉反应

    Cow

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KRT17 (Keratin 17 (KRT17))

    别名

    KRT17

    背景

    Background: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial \"stem cells\". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

    Aliases: KRT17 antibody, Keratin antibody, type I cytoskeletal 17 antibody, Cytokeratin-17 antibody, CK-17 antibody, Keratin-17 antibody, K17 antibody

    UniProt

    A1L595
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