IFNK 抗体 (AA 24-195) (FITC)
Quick Overview for IFNK 抗体 (AA 24-195) (FITC) (ABIN7140832)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-195
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交叉反应
- Cow
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Bovine Interferon tau-1 protein (24-195AA)
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亚型
- IgG
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anti-Interferon, kappa (IFNK) (AA 35-129) antibody
IFNK 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Interferon, kappa (IFNK) (AA 28-207) antibodyIFNK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon, kappa (IFNK) (AA 35-129) antibodyIFNK 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon, kappa (IFNK) (AA 1-207) antibodyIFNK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interferon, kappa (IFNK) (AA 1-207) antibodyIFNK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IFNK (Interferon, kappa (IFNK))
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别名
- IFNT1
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背景
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Background: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
Aliases: IFNT1 antibody, Interferon tau-1 antibody, IFN-tau-1 antibody, Antiluteolysin antibody, Trophoblast antiluteolytic protein antibody, Trophoblast protein 1 antibody, TP-1 antibody, Trophoblastin antibody
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UniProt
- P15696
抗原
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