PtxA (AA 35-269) 抗体
This 兔 多克隆 antibody specifically detects PtxA in ELISA 和 WB. It exhibits reactivity toward Bordetella pertussis.
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产品编号 ABIN7140770
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for PtxA (AA 35-269) 抗体 (ABIN7140770)
抗原
PtxA
适用
Bordetella pertussis
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 35-269
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原理
- ptxA Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PtxA
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背景
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Background: S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD+ into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
Aliases: ptxA antibody, BP3783 antibody, Pertussis toxin subunit 1 antibody, PTX S1 antibody, Islet-activating protein S1 antibody, IAP S1 antibody, NAD-dependent ADP-ribosyltransferase antibody, EC 2.4.2.- antibody
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UniProt
- P04977
抗原
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