ADCY1 抗体 (AA 1-358) (HRP)
Quick Overview for ADCY1 抗体 (AA 1-358) (HRP) (ABIN7140392)
抗原
See all ADCY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-358
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交叉反应
- African cassava mosaic virus (ACMV)
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant African cassava mosaic virus Replication-associated protein (1-358AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))
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别名
- AC1
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背景
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Background: Essential for the replication of viral ssDNA. The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific region at the genome origin of replication. It introduces an endonucleolytic nick within the conserved sequence 5\'-TAATATTAC-3\' in the intergenic region of the genome present in all geminiviruses, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5\'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3\'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
Aliases: AC1 antibody, AL1 antibody, Replication-associated protein antibody, Rep antibody, EC 2.7.7.- antibody, EC 3.1.21.- antibody, 40.4 kDa protein antibody, Protein AC1 antibody, Protein AL1 antibody
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UniProt
- P14982
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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