WDR77 抗体
Quick Overview for WDR77 抗体 (ABIN7140359)
抗原
See all WDR77 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Affinity purified
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免疫原
- Purified recombinant human WDR77 protein fragments expressed in E.coli.
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亚型
- IgG1, IgG1 kappa
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应用备注
- Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- WDR77 (WD Repeat Domain 77 (WDR77))
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别名
- WDR77
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背景
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Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
Aliases: 2610312E17Rik, Androgen receptor cofactor p44, C79984, HKMT1069, MEP 50, MEP-50, MEP50, MEP50_HUMAN, Methylosome protein 50, MGC2722, Nbla10071, p44, p44/Mep50, RGD1310479, RP11 552M11.3, WD repeat containing protein 77, WD repeat domain 77,
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UniProt
- Q9BQA1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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