CBR1 抗体
Quick Overview for CBR1 抗体 (ABIN7140302)
抗原
See all CBR1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Affinity purified
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免疫原
- Purified recombinant human CBR1 protein fragments expressed in E.coli
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亚型
- IgG1, IgG1 kappa
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应用备注
- Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified mouse monoclonal in PBS( pH 7.4)containing with 0.2 % sodium azide,50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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别名
- CBR1
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背景
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Background: NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Aliases: 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1, Carbonyl Reductase 1, CBR 1, CBR1, CBR1_HUMAN, CRN, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1,
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UniProt
- P16152
抗原
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