INPP5F 抗体 (AA 187-204)
Quick Overview for INPP5F 抗体 (AA 187-204) (ABIN7140040)
抗原
See all INPP5F 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 187-204
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)
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亚型
- IgG
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anti-Inositol Polyphosphate-5-Phosphatase F (INPP5F) antibody
KO Validated INPP5F 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase F (INPP5F) (AA 1-1132) antibodyINPP5F 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))
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别名
- INPP5F
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背景
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Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).
Aliases: INPP5F antibody, KIAA0966 antibody, SAC2 antibody, MSTP007 antibody, MSTP047 antibody, Phosphatidylinositide phosphatase SAC2 antibody, EC 3.1.3.25 antibody, Inositol polyphosphate 5-phosphatase F antibody, Sac domain-containing inositol phosphatase 2 antibody, Sac domain-containing phosphoinositide 4-phosphatase 2 antibody, hSAC2 antibody
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UniProt
- Q9Y2H2
抗原
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