INPP5F 抗体 (AA 187-204)
Our Local Distributor
北京 101111
Quick Overview for INPP5F 抗体 (AA 187-204) (ABIN7140040)
抗原
See all INPP5F 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 187-204
-
原理
- INPP5F Antibody
-
纯化方法
- Protein G purified
-
纯度
- >95 %
-
免疫原
- Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)
-
亚型
- IgG
-
-
anti-Inositol Polyphosphate-5-Phosphatase F (INPP5F) antibody
KO Validated INPP5F 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase F (INPP5F) (AA 1-1132) antibodyINPP5F 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))
-
别名
- INPP5F
-
背景
-
Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).
Aliases: INPP5F antibody, KIAA0966 antibody, SAC2 antibody, MSTP007 antibody, MSTP047 antibody, Phosphatidylinositide phosphatase SAC2 antibody, EC 3.1.3.25 antibody, Inositol polyphosphate 5-phosphatase F antibody, Sac domain-containing inositol phosphatase 2 antibody, Sac domain-containing phosphoinositide 4-phosphatase 2 antibody, hSAC2 antibody
-
UniProt
- Q9Y2H2
抗原
-
