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MDFIC 抗体 (AA 35-53) (Biotin)

This anti-MDFIC antibody is a 兔 多克隆 antibody detecting MDFIC in ELISA. Suitable for 人.
产品编号 ABIN7139929
发货至: 中国

Quick Overview for MDFIC 抗体 (AA 35-53) (Biotin) (ABIN7139929)

抗原

See all MDFIC 抗体
MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

适用

  • 26
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宿主

  • 26

克隆类型

  • 26
多克隆

标记

  • 13
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  • 1
  • 1
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This MDFIC antibody is conjugated to Biotin

应用范围

  • 17
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
ELISA
  • 抗原表位

    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 35-53

    原理

    MDFIC Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Peptide sequence from Human MyoD family inhibitor domain-containing protein (35-53AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

    别名

    MDFIC

    背景

    Background: Acts as a transcriptional activator or repressor. Inhibits the transcriptional activation of Zic family proteins ZIC1, ZIC2 and ZIC3. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm. Modulates the expression from both cellular and viral promoters. Down-regulates Tat-dependent transcription of the human immunodeficiency virus type 1 (HIV-1) LTR by interacting with HIV-1 Tat and Rev and impairing their nuclear import, probably by rendering the NLS domains inaccessible to importin-beta. Also stimulates activation of human T-cell leukemia virus type I (HTLV-I) LTR. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

    Aliases: MDFIC antibody, MyoD family inhibitor domain-containing protein antibody, I-mfa domain-containing protein antibody, hIC antibody

    UniProt

    Q9P1T7
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