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AJUBA 抗体 (AA 61-77) (HRP)

AJUBA 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7139907
发货至: 中国
  • 抗原 See all AJUBA 抗体
    AJUBA (Ajuba LIM Protein (AJUBA))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 61-77
    适用
    • 13
    • 2
    • 1
    • 1
    • 1
    宿主
    • 9
    • 3
    • 1
    克隆类型
    • 12
    • 1
    多克隆
    标记
    • 11
    • 1
    • 1
    This AJUBA antibody is conjugated to HRP
    应用范围
    • 9
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Peptide sequence from Human LIM domain-containing protein ajuba protein (61-77AA)
    亚型
    IgG
    Top Product
    Discover our top product AJUBA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    AJUBA (Ajuba LIM Protein (AJUBA))
    别名
    AJUBA (AJUBA 产品)
    别名
    JUB antibody, Jub antibody, ajuba LIM protein antibody, AJUBA antibody, Ajuba antibody
    背景

    Background: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an important role in regulation of the kinase activity of AURKA for mitotic commitment. Also a component of the IL-1 signaling pathway modulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex. Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1.

    Aliases: AJUBA antibody, JUB antibody, LIM domain-containing protein ajuba antibody

    UniProt
    Q96IF1
    途径
    Chromatin Binding, Cell-Cell Junction Organization
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