IgG3 抗体 (AA 312-324) (Biotin)
Quick Overview for IgG3 抗体 (AA 312-324) (Biotin) (ABIN7139884)
抗原
See all IgG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 312-324
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Peptide sequence from Human Immunoglobulin heavy constant gamma 3 protein (312-324AA)
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亚型
- IgG
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anti-IgG3 (AA 1-521) antibody
适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IgG3 (AA 312-324) antibody适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-IgG3 antibody适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- IgG3
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别名
- IGHG3
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物质类
- Antibody
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背景
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Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Aliases: IGHG3Immunoglobulin heavy constant gamma 3 antibody, HDC antibody, Heavy chain disease protein antibody, Ig gamma-3 chain C region antibody
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UniProt
- P01860
抗原
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