AMOTL2 抗体 (AA 718-737)
Quick Overview for AMOTL2 抗体 (AA 718-737) (ABIN7139725)
抗原
See all AMOTL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 718-737
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交叉反应
- 人
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纯化方法
- Antigen Affinity Purified
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免疫原
- Peptide sequence from Human Angiomotin-like protein 2 protein (718-737AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:1000-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AMOTL2 (Angiomotin Like 2 (AMOTL2))
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别名
- AMOTL2
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背景
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Background: Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.
Aliases: AMOL2_HUMAN antibody, Amotl2 antibody, angiomotin like 2 antibody, Angiomotin-like protein 2 antibody, KIAA0989 antibody, LCCP antibody, Leman coiled coil protein antibody, Leman coiled-coil protein antibody
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UniProt
- Q9Y2J4
抗原
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