Paxillin 抗体 (pTyr88)
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北京 101111
Quick Overview for Paxillin 抗体 (pTyr88) (ABIN7139085)
抗原
See all Paxillin (PXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr88
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原理
- Phospho-PXN (Tyr88) Antibody
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 88 (P-V-Y(p)-G-S) derived from Human Paxillin.
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亚型
- IgG
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anti-Paxillin (PXN) (AA 201-461) antibody
PXN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (AA 347-578) antibodyPXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (AA 1-262) antibodyPXN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (AA 327-568) antibodyPXN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (AA 456-472) antibodyPXN 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) antibodyKD Validated PXN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2690 unconjugated Recombinant Antibody
anti-Paxillin (PXN) (AA 456-472), (C-Term) antibodyPXN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (pTyr118) antibodyPXN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (AA 1-262) antibodyPXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Paxillin (PXN) (pSer178) antibodyPXN 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Paxillin (PXN)
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别名
- PXN
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背景
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Background: An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions
Turner, C.E. (2000) J. Cell Sci. 113, 4139-4140
Burridge, K. et al. (1992) J. Cell Biol. 119, 893-903.
Bellis, S. L. et al. (1997) Biochem. J. 325, 375-381.Aliases: FLJ16691 antibody, FLJ23042 antibody, Paired box protein Pax 1 antibody, PAX 1 antibody, PAX1 antibody, PAXI_HUMAN antibody, Paxillin alpha antibody, Paxillin antibody, PXN antibody, PXN protein antibody
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UniProt
- P49023
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途径
- MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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