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Vinculin 抗体 (pTyr822)

The 兔 多克隆 anti-Vinculin antibody (ABIN7139077) specifically detects Vinculin in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7139077
发货至: 中国
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Quick Overview for Vinculin 抗体 (pTyr822) (ABIN7139077)

抗原

See all Vinculin (VCL) 抗体
Vinculin (VCL)

适用

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宿主

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克隆类型

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多克隆

标记

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This Vinculin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pTyr822

    原理

    Phospho-VCL (Tyr822) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Tyrosine 822 (S-G-Y(p)-R-I) derived from Human Vinculin.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Vinculin (VCL)

    别名

    VCL

    背景

    Background:

    Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

    Subauste MC, et al. (2004) J Cell Biol 165, 371-81
    Olsen JV, et al. (2010) Sci Signal 3, ra3
    J?rgensen C, et al. (2009) Science 326, 1502-9

    Aliases: CMD1W antibody, CMH15 antibody, Epididymis luminal protein 114 antibody, HEL114 antibody, Metavinculin antibody, MV antibody, MVCL antibody, OTTHUMP00000019861 antibody, OTTHUMP00000019862 antibody, VCL antibody, VINC antibody, VINC_HUMAN antibody, Vinculin antibody

    UniProt

    P18206

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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