Vinculin 抗体 (pTyr822)
Quick Overview for Vinculin 抗体 (pTyr822) (ABIN7139077)
抗原
See all Vinculin (VCL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr822
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Tyrosine 822 (S-G-Y(p)-R-I) derived from Human Vinculin.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Vinculin (VCL)
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别名
- VCL
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背景
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Background:
Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Subauste MC, et al. (2004) J Cell Biol 165, 371-81
Olsen JV, et al. (2010) Sci Signal 3, ra3
J?rgensen C, et al. (2009) Science 326, 1502-9Aliases: CMD1W antibody, CMH15 antibody, Epididymis luminal protein 114 antibody, HEL114 antibody, Metavinculin antibody, MV antibody, MVCL antibody, OTTHUMP00000019861 antibody, OTTHUMP00000019862 antibody, VCL antibody, VINC antibody, VINC_HUMAN antibody, Vinculin antibody
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UniProt
- P18206
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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