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ZAP70 抗体 (pTyr493)

This anti-ZAP70 antibody is a 兔 多克隆 antibody detecting ZAP70 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7139014
发货至: 中国

Quick Overview for ZAP70 抗体 (pTyr493) (ABIN7139014)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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宿主

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克隆类型

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多克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    pTyr493

    原理

    Phospho-ZAP70 (Tyr493) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 493 (S-Y-Y(p)-T-A) derived from Human Zap-70.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    Background: Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not.

    Chan AC, et al. (1995) EMBO J, 14(11): 2499-2508
    Kong G, et al. (1996) Mol Cell Biol, 16(9): 5026-5035
    Salomon AR, et al. (2003)Proc Natl Acad Sci U S A, 100(2): 443-448

    Aliases: 70 kDa zeta associated protein antibody, 70 kDa zeta-associated protein antibody, EC 2.7.10.2 antibody, FLJ17670 antibody, FLJ17679 antibody, Selective T cell defect antibody, SRK antibody, STD antibody, Syk related tyrosine kinase antibody, Syk-related tyrosine kinase antibody, Truncated ZAP kinase antibody, Tyrosine protein kinase ZAP70 antibody, Tyrosine-protein kinase ZAP-70 antibody, TZK antibody, ZAP 70 antibody, ZAP70 antibody, ZAP70_HUMAN antibody, Zeta chain associated protein kinase 70kD antibody, Zeta chain associated protein kinase 70 kDa antibody, Zeta chain associated protein kinase 70 kDa isoform 1 antibody, Zeta chain associated protein kinase 70 kDa isoform 2 antibody, Zeta chain of T cell receptor associated protein kinase 70 antibody, Zeta chain TCR associated protein kinase 70kD antibody, Zeta chain TCR associated protein kinase 70 kDa antibody

    UniProt

    P43403

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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