FGFR1/FGFR2 抗体 (pTyr463, pTyr466)
Quick Overview for FGFR1/FGFR2 抗体 (pTyr463, pTyr466) (ABIN7139009)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr463, pTyr466
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交叉反应
- 人, 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 463/466(S-E-Y(p)-E-L) derived from Human FGFR1/2.
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亚型
- IgG
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anti-FGFR1, FGFR2 (pTyr463), (pTyr466) antibody
适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-FGFR1, FGFR2 (pTyr463), (pTyr466) antibody适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FGFR1, FGFR2 (Tyr463), (Tyr466) antibody适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FGFR1/FGFR2 (FGFR1, FGFR2)
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别名
- FGFR1/FGFR2
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背景
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Background:
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Itoh N., Biochem. Biophys. Res. Commun. 169:680-685(1990).
Dionne C.A., EMBO J. 9:2685-2692(1990).
Johnson D.E., Mol. Cell. Biol. 10:4728-4736(1990).Aliases: Basic fibroblast growth factor receptor 1 antibody, bFGF-R-1 antibody, BFGFR antibody, CD331 antibody, CEK antibody, FGFBR antibody, FGFR 1 antibody, FGFR-1 antibody, FGFR1 antibody, FGFR1/PLAG1 fusion antibody, FGFR1_HUMAN antibody, fibroblast growth factor receptor 1 antibody, FLG antibody, FLT-2 antibody, FLT2 antibody, Fms-like gene antibody, Fms-like tyrosine kinase 2 antibody, fms-related tyrosine kinase 2 antibody, HBGFR antibody, heparin-binding growth factor receptor antibody, HH2 antibody, HRTFDS antibody, hydroxyaryl-protein kinase antibody, KAL2 antibody, N-SAM antibody, OGD antibody, Proto-oncogene c-Fgr antibody
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UniProt
- P11362
抗原
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