HCLS1 抗体 (pTyr397)
Quick Overview for HCLS1 抗体 (pTyr397) (ABIN7138997)
抗原
See all HCLS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr397
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交叉反应
- 人
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 .
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))
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别名
- HCLS1
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背景
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Background:
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.
Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T., Nat. Genet. 36:40-45(2004).Aliases: Cortactin like antibody, CTTNL antibody, HCLS 1 antibody, Hcls1 antibody, HCLS1_HUMAN antibody, Hematopoietic cell specific Lyn substrate 1 antibody, Hematopoietic cell-specific LYN substrate 1 antibody, Hematopoietic lineage cell-specific protein antibody, HS 1 antibody, HS1 antibody, LckBP1 antibody, OTTHUMP00000215180 antibody, OTTHUMP00000215182 antibody, p75 antibody
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UniProt
- P14317
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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