DOK2 抗体 (pTyr299)
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- 抗原 See all DOK2 抗体
- DOK2
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抗原表位
- pTyr299
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- 免疫原
- Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
- 亚型
- IgG
- Top Product
- Discover our top product DOK2 Primary Antibody
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- 应用备注
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DOK2
- 别名
- DOK2 (DOK2 产品)
- 背景
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Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody
- UniProt
- O60496
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