DOK2 抗体 (pTyr299)
Our Local Distributor
北京 101111
Quick Overview for DOK2 抗体 (pTyr299) (ABIN7138971)
抗原
See all DOK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr299
-
原理
- Phospho-DOK2 (Tyr299) Antibody
-
纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
-
免疫原
- Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- DOK2
-
别名
- DOK2
-
背景
-
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody
-
UniProt
- O60496
抗原
-