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DOK2 抗体 (pTyr299)

This anti-DOK2 antibody is a 兔 多克隆 antibody detecting DOK2 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7138971
发货至: 中国
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Quick Overview for DOK2 抗体 (pTyr299) (ABIN7138971)

抗原

See all DOK2 抗体
DOK2

适用

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宿主

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克隆类型

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多克隆

标记

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This DOK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    pTyr299

    原理

    Phospho-DOK2 (Tyr299) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    DOK2

    别名

    DOK2

    背景

    Background:

    DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

    Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
    Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
    Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
    Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.

    Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody

    UniProt

    O60496
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