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Caveolin-1 抗体 (pTyr14)

This anti-Caveolin-1 antibody is a 兔 多克隆 antibody detecting Caveolin-1 in WB, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138938
发货至: 中国

Quick Overview for Caveolin-1 抗体 (pTyr14) (ABIN7138938)

抗原

See all Caveolin-1 (CAV1) 抗体
Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

适用

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宿主

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克隆类型

  • 105
  • 32
多克隆

标记

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This Caveolin-1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    • 1
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    • 1
    • 1
    • 1
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    • 1
    pTyr14

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 14 (H-L-Y(p)-T-V) derived from Human CAVEOLIN-1.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

    别名

    CAV1

    背景

    Background: The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (a and beta) are encoded by a single transcript from this gene.

    Zhang Y, et al. (2005) Mol Cell Proteomics. 4(9): 1240-1250.
    Labrecque L, et al. (2004) J Biol Chem. 279(50): 52132-52140.
    Fielding PE, et al. (2004) Biochemistry. 43(9): 2578-2586.
    Labrecque L, et al. (2003) Mol Biol Cell. 14(1): 334-347.
    Maggi D, et al. (2002) Biochem Biophys Res Commun. 295(5): 1085-1089.

    Aliases: BSCL3 antibody, CAV antibody, CAV1 antibody, CAV1_HUMAN antibody, caveolae protein, 22 kD antibody, caveolin 1 alpha isoform antibody, caveolin 1 beta isoform antibody, Caveolin 1 caveolae protein 22 kDa antibody, Caveolin-1 antibody, Caveolin1 antibody, cell growth-inhibiting protein 32 antibody, CGL3 antibody, LCCNS antibody, MSTP085 antibody, OTTHUMP00000025031 antibody, PPH3 antibody, VIP 21 antibody, VIP21 antibody

    UniProt

    Q03135

    途径

    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
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