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MEF2A 抗体 (pThr319)

This anti-MEF2A antibody is a 兔 多克隆 antibody detecting MEF2A in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138767
发货至: 中国

Quick Overview for MEF2A 抗体 (pThr319) (ABIN7138767)

抗原

See all MEF2A 抗体
MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

适用

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宿主

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克隆类型

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多克隆

标记

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This MEF2A antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
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    pThr319

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Thr319 (V-T-T(p)-P-S) derived from Human MEF2A.

    亚型

    IgG
  • 应用备注

    IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

    别名

    MEF2A

    背景

    Background: The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain

    Shore, P. et al. (1995) Eur. J. Biochem. 229, 1-13
    Martin, J.F. et al. (1994) Mol. Cell. Biol. 14, 1647-1656
    Yu, Y.T. et al. (1992) Genes Dev. 6, 1783-1798
    Zhao, M. et al. (1999) Mol. Cell. Biol. 19, 21-30

    Aliases: ADCAD1 antibody, MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody, MEF2 antibody, MEF2A antibody, MEF2A_HUMAN antibody, Myocyte enhancer factor 2A antibody, Myocyte-specific enhancer factor 2A antibody, RSRFC4 antibody, RSRFC9 antibody, Serum response factor like protein 1 antibody, Serum response factor-like protein 1 antibody

    UniProt

    Q02078

    途径

    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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