PKMYT1 抗体 (pSer83)
Quick Overview for PKMYT1 抗体 (pSer83) (ABIN7138712)
抗原
See all PKMYT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer83
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交叉反应
- 人
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.
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亚型
- IgG
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应用备注
- IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
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别名
- PKMYT1
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背景
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Background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Booher R.N., J. Biol. Chem. 272:22300-22306(1997).
Liu F., Mol. Cell. Biol. 17:571-583(1997).
Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).Aliases: cdc2 inhibitory kinase antibody, DKFZp547K1610 antibody, FLJ20093 antibody, Membrane associated tyrosine and threonine specific cdc2 inhibitory kinase antibody, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase antibody, MYT1 antibody, Myt1 kinase antibody, PKMYT 1 antibody, Pkmyt1 antibody, PMYT1_HUMAN antibody, PPP1R126 antibody, Protein kinase membrane associated tyrosine/threonine 1 antibody, Protein kinase Myt1 antibody, Protein phosphatase 1 regulatory subunit 126 antibody
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UniProt
- Q99640
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途径
- Mitotic G1-G1/S Phases, M Phase
抗原
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