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PKMYT1 抗体 (pSer83)

This 兔 多克隆 anti-PKMYT1 antibody specifically detects PKMYT1 in ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN7138712
发货至: 中国
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Quick Overview for PKMYT1 抗体 (pSer83) (ABIN7138712)

抗原

See all PKMYT1 抗体
PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

适用

  • 88
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宿主

  • 85
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克隆类型

  • 85
  • 3
多克隆

标记

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This PKMYT1 antibody is un-conjugated

应用范围

  • 71
  • 39
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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 22
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    pSer83

    原理

    Phospho-PKMYT1 (Ser83) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

    别名

    PKMYT1

    背景

    Background:

    The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Booher R.N., J. Biol. Chem. 272:22300-22306(1997).
    Liu F., Mol. Cell. Biol. 17:571-583(1997).
    Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).

    Aliases: cdc2 inhibitory kinase antibody, DKFZp547K1610 antibody, FLJ20093 antibody, Membrane associated tyrosine and threonine specific cdc2 inhibitory kinase antibody, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase antibody, MYT1 antibody, Myt1 kinase antibody, PKMYT 1 antibody, Pkmyt1 antibody, PMYT1_HUMAN antibody, PPP1R126 antibody, Protein kinase membrane associated tyrosine/threonine 1 antibody, Protein kinase Myt1 antibody, Protein phosphatase 1 regulatory subunit 126 antibody

    UniProt

    Q99640

    途径

    Mitotic G1-G1/S Phases, M Phase
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