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KRT8 抗体 (pSer74)

The 兔 多克隆 anti-KRT8 antibody (ABIN7138693) specifically detects KRT8 in WB, IF 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7138693
发货至: 中国
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Quick Overview for KRT8 抗体 (pSer74) (ABIN7138693)

抗原

See all KRT8 抗体
KRT8 (Keratin 8 (KRT8))

适用

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宿主

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克隆类型

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多克隆

标记

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This KRT8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA
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    pSer74

    原理

    Phospho-KRT8 (Ser74) Antibody

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 74 (L-L-S(p)-P-L) derived from Human Keratin 8 (CK8).

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    KRT8 (Keratin 8 (KRT8))

    别名

    KRT8

    背景

    Background:

    Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

    Nakamichi I, et al. (2002) Mol Biol Cell, 13(10): 3441-3451.
    Prochasson P, et al. (2002) Nucleic Acids Res, 30(15): 3312-3322.
    Pankov R, et al. (1994) Proc Natl Acad Sci U S A, 91(3): 873-877.
    Thorey IS, et al. (1993) Mol Cell Biol, 13(11): 6742-6751

    Aliases: CARD2 antibody, CK 8 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, CYKER antibody, Cytokeratin endo A antibody, Cytokeratin-8 antibody, DreK8 antibody, EndoA antibody, K2C8 antibody, K2C8_HUMAN antibody, K8 antibody, Keratin 8 antibody, Keratin type II cytoskeletal 8 antibody, Keratin, type II cytoskeletal 8 antibody, Keratin-8 antibody, KO antibody, Krt 2.8 antibody, KRT8 antibody, MGC118110 antibody, MGC174782 antibody, MGC53564 antibody, MGC85764 antibody, sb:cb186 antibody, Type-II keratin Kb8 antibody

    UniProt

    P05787
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