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PDCD4 抗体 (pSer67)

This anti-PDCD4 antibody is a 兔 多克隆 antibody detecting PDCD4 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138677
发货至: 中国

Quick Overview for PDCD4 抗体 (pSer67) (ABIN7138677)

抗原

See all PDCD4 抗体
PDCD4 (Programmed Cell Death 4 (PDCD4))

适用

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宿主

  • 92
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克隆类型

  • 87
  • 15
多克隆

标记

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This PDCD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pSer67

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 67 (K-N-S(p)-S-R) derived from Human PDCD4 .

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PDCD4 (Programmed Cell Death 4 (PDCD4))

    别名

    PDCD4

    背景

    Background:

    Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA

    Kakade D, Islam N, Maeda N, Adegoke OA (2014)BMC Cell Biol 15, 2 . Dorrello NV, et al. (2006)Science 314, 467-71. Palamarchuk A, et al. (2005)Cancer Res 65, 11282-6.

    Aliases: Death up-regulated gene protein antibody, Dug antibody, H731 antibody, Ma3 antibody, MGC33046 antibody, MGC33047 antibody, Neoplastic transformation inhibitor antibody, Neoplastic transformation inhibitor protein antibody, Nuclear antigen H731 antibody, Nuclear antigen H731 like antibody, Nuclear antigen H731 like protein antibody, Nuclear antigen H731-like antibody, PDCD 4 antibody, Pdcd4 antibody, PDCD4_HUMAN antibody, Programmed cell death 4 antibody, programmed cell death 4 (neoplastic transformation inhibitor) antibody, Programmed cell death protein 4 antibody, Protein 197/15a antibody, Protein MA-3 antibody, Tis antibody, Topoisomerase-inhibitor suppressed protein antibody

    UniProt

    Q53EL6
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