HDAC4 抗体 (pSer632)
Quick Overview for HDAC4 抗体 (pSer632) (ABIN7138666)
抗原
See all HDAC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer632
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of serine 632 (A-Q-S(p)-S-P) derived from Human HDAC4.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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别名
- HDAC4
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背景
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Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Wang AH, et al. (2000) Mol Cell Biol. 20(18): 6904-6912.
Grozinger CM, et al. (2000) Proc Natl Acad Sci U S A. 97(14): 7835-7840.
Aliases: AHO3 antibody; BDMR antibody; EC 3.5.1.98 antibody; HA6116 antibody; HD 4 antibody; HD4 antibody; HDAC 4 antibody; HDAC A antibody; HDAC4 antibody; HDAC4_HUMAN antibody; HDACA antibody; Histone deacetylase 4 antibody; Histone Deacetylase A antibody; KIAA0288 antibody
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UniProt
- P56524
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
抗原
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