EIF2S1 抗体 (pSer51)
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北京 101111
Quick Overview for EIF2S1 抗体 (pSer51) (ABIN7138638)
抗原
See all EIF2S1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer51
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原理
- Phospho-EIF2S1 (Ser51) Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of serine 51 (E-L-S(p)-R-R) derived from Human eIF2a.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibody
EIF2S1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) antibodyEIF2S1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (N-Term) antibodyEIF2S1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1C6 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer49) antibodyEIF2S1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 276-315) antibodyEIF2S1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (C-Term) antibodyEIF2S1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 犬, Pig, 猴, 小鸡, 兔, 豚鼠, 马, 山羊, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
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别名
- EIF2S1
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背景
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Background:
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Xavier Saelens, et al. (2001) J. Biol. Chem, 276: 41620 - 41628.
Hiroyuki Kubota, et al. (2003) J. Biol. Chem , 278: 20457 - 20460.
Shijian Chu, et al. (2006) Am J Physiol Lung Cell Mol Physiol , 291: L983 - L992.
Eileen Connolly, et al. (2006) Mol. Cell. Biol , 26: 3955 - 3965.Aliases: EIF 2 alpha antibody, EIF 2 antibody, EIF 2A antibody, EIF 2alpha antibody, eIF-2-alpha antibody, eIF-2A antibody, EIF-2alpha antibody, EIF2 alpha antibody, EIF2 antibody, EIF2A antibody, EIF2S1 antibody, Eukaryotic translation initiation factor 2 subunit 1 alpha 35 kDa antibody, Eukaryotic translation initiation factor 2 subunit 1 alpha antibody, Eukaryotic translation initiation factor 2 subunit 1 antibody, Eukaryotic translation initiation factor 2 subunit alpha antibody, IF2A_HUMAN antibody
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UniProt
- P05198
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途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
抗原
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