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EIF4B 抗体 (pSer422)

The 兔 多克隆 anti-EIF4B antibody is suitable to detect EIF4B in samples from 人. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7138611
发货至: 中国
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Quick Overview for EIF4B 抗体 (pSer422) (ABIN7138611)

抗原

See all EIF4B 抗体
EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

适用

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宿主

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克隆类型

  • 85
  • 34
多克隆

标记

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This EIF4B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    pSer422

    原理

    Phospho-EIF4B (Ser422) Antibody

    交叉反应

    小鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 422 (T-G-S(p)-E-S) derived from Human eIF4B.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

    别名

    EIF4B

    背景

    Background: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

    Gingras, A.C. et al. (2001) Genes Dev. 15, 807-826.
    Duncan, R. and Hershey, J.W. (1985) J. Biol. Chem. 260, 5493-5497.
    Duncan, R.F. and Hershey, J.W. (1989) J. Cell Biol. 109, 1467-1481.

    Aliases: 2310046H11Rik antibody, AL024095 antibody, C85189 antibody, EIF 4B antibody, eIF-4B antibody, EIF4B antibody, Eukaryotic initiation factor 4B antibody, Eukaryotic translation initiation factor 4B antibody, IF4B_HUMAN antibody, PRO1843 antibody

    UniProt

    P23588
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