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FBXL3 抗体 (pSer320)

This anti-FBXL3 antibody is a 兔 多克隆 antibody detecting FBXL3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138554
发货至: 中国

Quick Overview for FBXL3 抗体 (pSer320) (ABIN7138554)

抗原

See all FBXL3 抗体
FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

适用

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宿主

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克隆类型

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多克隆

标记

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This FBXL3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pSer320

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 320 (S-V-S(p)-K-D) derived from Human FBXL3.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))

    别名

    FBXL3

    背景

    Background:

     Substrate-recognition component of the SCF(FBXL3) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL3) complex mainly acts in the nucleus and mediates ubiquitination and subsequent degradation of CRY1 and CRY2. Activity of the SCF(FBXL3) complex is counteracted by the SCF(FBXL21) complex.

     
    1)Busino L., Bassermann F., Maiolica A., Lee C., Nolan P.M., Godinho S.I., Draetta G.F., Pagano M. Science 316:900-904(2007)                                          
    2)Yoo S.H., Mohawk J.A., Siepka S.M., Shan Y., Huh S.K., Hong H.K., Kornblum I., Kumar V., Koike N., Xu M., Nussbaum J., Liu X., Chen Z., Chen Z.J., Green C.B., Takahashi J.S.Cell 152:1091-1105(2013)
     

    Aliases: F box and leucine rich repeat protein 3 antibody; F box and leucine rich repeat protein 3A antibody; F box protein Fbl3a antibody; F-box and leucine-rich repeat protein 3A antibody; F-box/LRR-repeat protein 3 antibody; F-box/LRR-repeat protein 3A antibody; FBL3 antibody; FBL3A antibody; Fbxl3 antibody; FBXL3_HUMAN antibody; FBXL3A antibody

    UniProt

    Q9UKT7

    途径

    Photoperiodism
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