G3BP1 抗体 (pSer232)
Quick Overview for G3BP1 抗体 (pSer232) (ABIN7138496)
抗原
See all G3BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer232
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原理
- Phospho-G3BP1 (Ser232) Antibody
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of serine 232 (S-S-S(p)-P-A) derived from Human G3BP-1.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))
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别名
- G3BP1
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背景
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Background: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Tao WA, et al. (2005) Nat Methods. 2(8): 591-598.
Zheng H, et al. (2005) Mol Cell Proteomics. 4(6):721-730.
Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A.101 (33): 12130-12135.
Tourrihre H, et al. (2003) J Cell Biol.160 (6): 823-831.Aliases: ATP dependent DNA helicase VIII antibody, ATP-dependent DNA helicase VIII antibody, G3BP antibody, G3BP stress granule assembly factor 1 antibody, G3BP-1 antibody, G3bp1 antibody, G3BP1_HUMAN antibody, GAP binding protein antibody, GAP SH3 domain binding protein 1 antibody, GAP SH3 domain-binding protein 1 antibody, GTPase activating protein (SH3 domain) binding protein 1 antibody, hDH VIII antibody, Human DNA helicase VIII antibody, MGC111040 antibody, Ras GTPase activating protein binding protein 1 antibody, Ras GTPase activating protein SH3 domain binding protein antibody, Ras GTPase-activating protein-binding protein 1 antibody, RasGAP associated endoribonuclease G3BP antibody
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UniProt
- Q13283
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途径
- SARS-CoV-2 Protein Interactome
抗原
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