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FOXO4 抗体 (pSer197)

This anti-FOXO4 antibody is a 兔 多克隆 antibody detecting FOXO4 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7138463
发货至: 中国

Quick Overview for FOXO4 抗体 (pSer197) (ABIN7138463)

抗原

See all FOXO4 抗体
FOXO4 (Forkhead Box O4 (FOXO4))

适用

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宿主

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克隆类型

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多克隆

标记

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This FOXO4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    pSer197

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of serine 197 (A-A-S(p)-M-D) derived from Human AFX.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FOXO4 (Forkhead Box O4 (FOXO4))

    别名

    FOXO4

    背景

    Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.

    Di Maira G, et al. (2005)Cell Death Differ, 12(6): 668-77.
    Essers MA, et al. EMBO J 2004 Nov. 11.
    Brownawell AM, (2001) Mol Cell Biol, 21(10): 3534-46.
    Kops GJ, et al. (1999) Nature, 398(6728): 630-4.

    Aliases: AFX antibody, AFX1 antibody, Afxh antibody, ALL1-fused gene from X chromosome antibody, Fork head domain transcription factor AFX1 antibody, Forkhead box O4 antibody, Forkhead box protein O4 antibody, FOXO 4 antibody, Foxo4 antibody, FOXO4_HUMAN antibody, MGC117660 antibody, MGC120490 antibody, Mixed lineage leukemia, translocated to, 7 antibody, MLLT7 antibody, Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila), translocated to, 7 antibody, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7 antibody, RGD1561201 antibody

    UniProt

    P98177

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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