Protein Tob1 (TOB1) (pSer164) 抗体
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Quick Overview for Protein Tob1 (TOB1) (pSer164) 抗体 (ABIN7138445)
抗原
See all Protein Tob1 (TOB1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer164
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原理
- Phospho-TOB1 (Ser164) Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Serine 164(A-V-S(p)-P-T) derived from Human TOB1.
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亚型
- IgG
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anti-Protein Tob1 (TOB1) (AA 42-175) antibody
TOB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (AA 1-345) antibodyTOB1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (Ser164) antibodyTOB1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (AA 54-83), (N-Term) antibodyTOB1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19906 unconjugated
anti-Protein Tob1 (TOB1) antibodyTOB1 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (AA 61-91), (N-Term) antibodyTOB1 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (pSer164) antibodyTOB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (AA 173-222) antibodyTOB1 适用: 小鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (AA 215-264) antibodyTOB1 适用: 人, 小鼠, Cow, 犬, 马, Drosophila melanogaster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Tob1 (TOB1) (Middle Region) antibodyTOB1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Protein Tob1 (TOB1)
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别名
- TOB1
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背景
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Background:
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Matsuda S., Oncogene 12:705-713(1996).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N., Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.Aliases: TOB1 antibody, TOB antibody, TROB1 antibody, Protein Tob1 antibody, Transducer of erbB-2 1 antibody
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UniProt
- P50616
抗原
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