CRY1 抗体
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- 抗原 See all CRY1 抗体
- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRY1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 小鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.
- 亚型
- IgG
- Top Product
- Discover our top product CRY1 Primary Antibody
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- 应用备注
- WB:1:500-1:3000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
- 别名
- CRY1 (CRY1 产品)
- 背景
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Background:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
Morioka N,et al. (2010) J Pharmacol Sci.113(3):234-45.
Fonseca F,et al. (2010) Mol Diagn Ther.14(3):171-8.
Stratmann M,et al.(2010) Genes Dev.24(12):1317-28.Aliases: Cry1 antibody, CRY1_HUMAN antibody, Cryptochrome 1 (photolyase like) antibody, Cryptochrome 1 antibody, Cryptochrome-1 antibody, PHLL1 antibody, Photolyase 1 antibody, Photolyase-like antibody
- UniProt
- Q16526
- 途径
- Response to Water Deprivation, Proton Transport
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