CPI-17 抗体
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北京 101111
Quick Overview for CPI-17 抗体 (ABIN7138212)
抗原
See all CPI-17 (PPP1R14A) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PPP1R14A (Ab-38) Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Peptide sequence around aa.36~40 (R-V-T-V-K) derived from Human CPI17a.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CPI-17 (PPP1R14A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A (PPP1R14A))
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别名
- PPP1R14A
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背景
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Background: Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Hagerty L, et al. (2007) J Biol Chem. 2007, 282(7):4884-93
Seok YM, et al. (2008) J Pharmacol Exp Ther.
Niiro N et al. (2003) Biochem J. 2003 ,369(Pt 1):117-28Aliases: 17 kDa PKC-potentiated inhibitory protein of PP1 antibody, 17-KDa protein antibody, 17 kDa PKC potentiated inhibitory protein of PP1 antibody, CPI 17 alpha antibody, CPI 17 antibody, CPI 17alpha antibody, CPI-17 antibody, CPI17 alpha antibody, CPI17 antibody, PKC potentiated inhibitory protein of PP1 antibody, PKC potentiated inhibitory protein of PP1, 17-KD antibody, PP14A_HUMAN antibody, PPP1INL antibody, Ppp1r14a antibody, Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD antibody, Protein kinase C-potentiated inhibitor protein of 17 kDa antibody, Protein phosphatase 1 antibody, Protein phosphatase 1 regulatory (inhibitor) subunit 14A antibody, Protein phosphatase 1 regulatory subunit 14A antibody, Regulatory subunit 14A antibody
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UniProt
- Q96A00
抗原
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