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TWIST2 抗体

TWIST2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138153
发货至: 中国
  • 抗原 See all TWIST2 抗体
    TWIST2 (Twist Homolog 2 (TWIST2))
    适用
    • 19
    • 10
    • 9
    宿主
    • 15
    • 4
    克隆类型
    • 15
    • 4
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TWIST2 antibody is un-conjugated
    应用范围
    • 10
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    Peptide sequence around aa.26~30(P-K-R-F-G) derived from Human Twist2.
    亚型
    IgG
    Top Product
    Discover our top product TWIST2 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TWIST2 (Twist Homolog 2 (TWIST2))
    别名
    TWIST2 (TWIST2 产品)
    别名
    TWIST2 antibody, DERMO1 antibody, FFDD3 antibody, SETLSS antibody, bHLHa39 antibody, Dermo1 antibody, CDERMO-1 antibody, twist family bHLH transcription factor 2 antibody, twist basic helix-loop-helix transcription factor 2 antibody, TWIST2 antibody, Twist2 antibody
    背景

    Background:

    Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

    Lee M.S., Lowe G., Flanagan S., Kuchler K., Glackin C.A.Bone 27:591-602(2000)

    Aliases: bHLHa39 antibody, Class A basic helix-loop-helix protein 39 antibody, Dermis expressed protein 1 antibody, Dermis-expressed protein 1 antibody, DERMO 1 antibody, Dermo-1 antibody, DERMO1 antibody, MGC117334 antibody, Twist 2 antibody, Twist homolog 2 (Drosophila) antibody, Twist homolog 2 antibody, Twist related bHLH protein Dermo1 antibody, Twist related protein 2 antibody, Twist-related protein 2 antibody, Twist2 antibody, TWST2_HUMAN antibody

    UniProt
    Q8WVJ9
    途径
    Chromatin Binding
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