Synaptoporin 抗体
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北京 101111
Quick Overview for Synaptoporin 抗体 (ABIN7138150)
抗原
See all Synaptoporin (SYNPR) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Synpr Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- Peptide sequence around aa.257~261(G-P-T-S-F)derived from Rat synaptophysin 2.
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亚型
- IgG
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anti-Synaptoporin (SYNPR) (AA 199-265) antibody
SYNPR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (C-Term) antibodySYNPR 适用: 人, 大鼠, 小鼠, Hamster WB, IHC, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 250-265) antibodySYNPR 适用: 大鼠, 小鼠, Hamster WB, IHC, IHC (p), ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 31-130) antibodySYNPR 适用: 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (AA 91-140) antibodySYNPR 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptoporin (SYNPR) (Middle Region) antibodySYNPR 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Synaptoporin (SYNPR)
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别名
- Synpr
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背景
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Background:
Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
Wiedenmann, B. et al. (1986) Proc Natl Acad Sci USA 83, 3500-4.
Valtorta, F. et al. (2004) Bioessays 26, 445-53.
Arthur, C.P. and Stowell, M.H. (2007) Structure 15, 707-14.
Bonanomi, D. et al. (2007) Biochem J 404, 525-34.Aliases: Synpr antibody, Synaptoporin antibody
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UniProt
- P22831
抗原
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