DAB1 抗体
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- 抗原 See all DAB1 抗体
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAB1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.
- 亚型
- IgG
- Top Product
- Discover our top product DAB1 Primary Antibody
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- 应用备注
- IHC:1:50-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))
- 别名
- DAB1 (DAB1 产品)
- 背景
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Background: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Kelian Chen, et,al. (2003) J. Cell Sci , 117: 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol , 24: 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE , 2003: 9.
H. M. Kim, et,al. (2002) PNAS , 99: 4020.Aliases: Dab 1 antibody, Dab reelin signal transducer 1 antibody, Dab, reelin signal transducer, homolog 1 (Drosophila) antibody, Dab1 antibody, DAB1_HUMAN antibody, Disabled homolog 1 antibody, Disabled homolog 1 Drosophila antibody, Scm antibody, Scr antibody, Scrambler antibody, Yot antibody, Yotari antibody
- UniProt
- O75553
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