TBC1D22A 抗体
Quick Overview for TBC1D22A 抗体 (ABIN7131302)
抗原
See all TBC1D22A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TBC1D22A Antibody
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交叉反应
- 小鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human TBC1D22A
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))
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别名
- TBC1D22A
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背景
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Background: TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
Aliases: TBC1D22A antibody, C22orf4 antibody, TBC1 domain family member 22A antibody
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UniProt
- Q8WUA7
抗原
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