PCP4 抗体
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北京 101111
Quick Overview for PCP4 抗体 (ABIN7130557)
抗原
See all PCP4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PCP4 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human PCP4
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亚型
- IgG
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anti-Purkinje Cell Protein 4 (PCP4) antibody
Microarray verified PCP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB311872 unconjugated
anti-Purkinje Cell Protein 4 (PCP4) antibodyMicroarray verified PCP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB193021 unconjugated
anti-Purkinje Cell Protein 4 (PCP4) antibodyMicroarray verified PCP4 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB821213 unconjugated
anti-Purkinje Cell Protein 4 (PCP4) (AA 1-62) antibodyPCP4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Purkinje Cell Protein 4 (PCP4) (AA 21-62) antibodyPCP4 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PCP4 (Purkinje Cell Protein 4 (PCP4))
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别名
- PCP4
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背景
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Background: PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.
Aliases: Brain specific antigen PCP 4 antibody, Brain specific polypeptide PEP 19 antibody, Brain specific polypeptide PEP19 antibody, Brain-specific antigen PCP-4 antibody, Brain-specific polypeptide PEP-19 antibody, OTTHUMP00000109191 antibody, Pcp4 antibody, PCP4_HUMAN antibody, PEP19 antibody, Purkinje cell protein 4 antibody
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UniProt
- P48539
抗原
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