LAT2 抗体
Quick Overview for LAT2 抗体 (ABIN7130064)
抗原
See all LAT2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human LAT2
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亚型
- IgG
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应用备注
- ELISA:1:1000-1:5000, IHC:1:10-1:50,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
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别名
- LAT2
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背景
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Background: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Aliases: HSPC046 antibody, LAB antibody, LAT2 antibody, Linker for activation of B cells antibody, Linker for activation of B-cells antibody, Linker for activation of T cells family member 2 antibody, Linker for activation of T cells transmembrane adaptor 2 antibody, Linker for activation of T-cells family member 2 antibody, Membrane associated adapter molecule antibody, Membrane-associated adapter molecule antibody, Non T cell activation linker antibody, Non-T-cell activation linker antibody, NTAL_HUMAN antibody, WBSCR 5 antibody, Wbscr15 antibody, Williams Beuren syndrome chromosome region 15 antibody, Williams Beuren syndrome chromosome region 5 antibody, Williams-Beuren syndrome chromosomal region 15 protein antibody, Williams-Beuren syndrome chromosomal region 5 protein antibody, WSCR5 antibody
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UniProt
- Q9GZY6
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途径
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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