ACOT8 抗体 (AA 31-130)
Quick Overview for ACOT8 抗体 (AA 31-130) (ABIN708641)
抗原
See all ACOT8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-130
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预测反应
- Human,Mouse,Rat,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ACOT8
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ACOT8 (Acyl-CoA Thioesterase 8 (ACOT8))
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别名
- ACOT8
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背景
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Synonyms: ACTEIII, Acot8, ACOT8_HUMAN, acyl CoA thioesterase 8, Acyl-CoA thioesterase 8, Acyl-coenzyme A thioesterase 8, Choloyl coenzyme A thioesterase, Choloyl-coenzyme A thioesterase, hACTE III, hACTE-III, hACTEIII, HIV Nef associated acyl CoA thioesterase, HIV-Nef-associated acyl-CoA thioesterase, HNAACTE, hTE, Long chain fatty acyl CoA hydrolase, Palmitoyl CoA hydrolase, Peroxisomal acyl CoA thioesterase 1, Peroxisomal acyl coenzyme A thioester hydrolase 1, Peroxisomal acyl-coenzyme A thioester hydrolase 1, Peroxisomal long chain acyl CoA thioesterase 1, Peroxisomal long-chain acyl-CoA thioesterase 1, PTE 1, PTE 2, PTE-1, PTE-2, PTE1, PTE2, Thioesterase II.
Background: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A Thioesterase 8, also known as ACOT8 may mediate Nef-induced down-regulation of CD4. It is a major thioesterase in peroxisomes and competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). It shows a preference for medium-length fatty acyl-CoAs and may be involved in the metabolic regulation of peroxisome proliferation.
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基因ID
- 10005
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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