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Recombinant WT1 抗体

This 兔 单克隆 antibody specifically detects WT1 in IHC, WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7127870
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant WT1 抗体 (ABIN7127870)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), ELISA

克隆位点

5F2
  • 原理

    WT1 Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Wilms Tumor Protein

    亚型

    IgG
  • 应用备注

    WB:1:500-1:5000, IHC:1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    WT1

    背景

    Background: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).

    Aliases: Wilms tumor protein (WT33), WT1

    UniProt

    P19544

    途径

    Tube Formation
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