Recombinant WT1 抗体
Quick Overview for Recombinant WT1 抗体 (ABIN7127870)
抗原
See all WT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human Wilms Tumor Protein
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- WT1 (Wilms Tumor 1 (WT1))
-
别名
- WT1
-
背景
-
Background: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).
Aliases: Wilms tumor protein (WT33), WT1
-
UniProt
- P19544
-
途径
- Tube Formation
抗原
-