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Recombinant SIRT5 抗体

SIRT5 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9H12 unconjugated Recombinant Antibody
产品编号 ABIN7127810
发货至: 中国
  • 抗原 See all SIRT5 抗体
    SIRT5 (Sirtuin 5 (SIRT5))
    抗体类型
    Recombinant Antibody
    适用
    • 84
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    • 31
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    • 5
    • 3
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    宿主
    • 83
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    克隆类型
    • 80
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    单克隆
    标记
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    This SIRT5 antibody is un-conjugated
    应用范围
    • 78
    • 39
    • 27
    • 15
    • 13
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    • 6
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    • 3
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    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human SIRT5
    克隆位点
    9H12
    亚型
    IgG
    Top Product
    Discover our top product SIRT5 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SIRT5 (Sirtuin 5 (SIRT5))
    别名
    SIRT5 (SIRT5 产品)
    别名
    SIR2L5 antibody, 0610012J09Rik antibody, 1500032M05Rik antibody, AV001953 antibody, zgc:92288 antibody, sirt5-a antibody, SIRT5 antibody, sir2l5 antibody, sirtuin 5 antibody, sirtuin 5 L homeolog antibody, SIRT5 antibody, Sirt5 antibody, sirt5 antibody, sirt5.L antibody, CC1G_00083 antibody
    背景

    Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.

    Aliases: NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5

    UniProt
    Q9NXA8
    途径
    SARS-CoV-2 Protein Interactome
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