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Recombinant SIRT5 抗体

This anti-SIRT5 antibody is a 兔 单克隆 antibody detecting SIRT5 in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7127810
发货至: 中国

Quick Overview for Recombinant SIRT5 抗体 (ABIN7127810)

抗原

See all SIRT5 抗体
SIRT5 (Sirtuin 5 (SIRT5))

抗体类型

Recombinant Antibody

适用

  • 92
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  • 5
  • 5
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  • 3
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宿主

  • 90
  • 12
  • 2
  • 2

克隆类型

  • 86
  • 20
单克隆

标记

  • 51
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  • 6
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  • 2
  • 1
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  • 1
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This SIRT5 antibody is un-conjugated

应用范围

  • 84
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  • 10
  • 6
  • 3
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  • 1
Immunohistochemistry (IHC), ELISA

克隆位点

9H12
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human SIRT5

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SIRT5 (Sirtuin 5 (SIRT5))

    别名

    SIRT5

    背景

    Background: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins (PubMed:21908771, PubMed:22076378, PubMed:24703693). Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting (PubMed:22076378, PubMed:24703693). Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species (PubMed:24140062). Modulates ketogenesis through the desuccinylation and activation of HMGCS2 (By similarity). Has weak NAD-dependent protein deacetylase activity, however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as UOX.

    Aliases: NAD-dependent protein deacylase sirtuin-5, mitochondrial (EC 3.5.1.-) (Regulatory protein SIR2 homolog 5) (SIR2-like protein 5), SIRT5, SIR2L5

    UniProt

    Q9NXA8

    途径

    SARS-CoV-2 Protein Interactome
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