Recombinant MFN2 抗体
Quick Overview for Recombinant MFN2 抗体 (ABIN7127622)
抗原
See all MFN2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human Mitofusin 2
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亚型
- IgG
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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 HRP
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Biotin
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应用备注
- Recommended dilution: IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- MFN2
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背景
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Background: Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:11181170, PubMed:11950885, PubMed:28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:28114303). Overexpression induces the formation of mitochondrial networks (PubMed:28114303). Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (By similarity). Plays an important role in the regulation of vascular smooth muscle cell proliferation (By similarity). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) (PubMed:23620051). Is required for PRKN recruitment to dysfunctional mitochondria (PubMed:23620051). Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress (By similarity). Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions (By similarity).
Aliases: Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2), MFN2, CPRP1 KIAA0214
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UniProt
- O95140
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途径
- Skeletal Muscle Fiber Development
抗原
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