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Recombinant HNRNPK 抗体

This 兔 单克隆 anti-HNRNPK antibody (Clone 3G7) specifically detects HNRNPK in WB, IHC, ELISA, IF 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7127548
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for Recombinant HNRNPK 抗体 (ABIN7127548)

抗原

See all HNRNPK 抗体
HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This HNRNPK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

3G7
  • 原理

    HNRNPK Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human HNRNPK

    亚型

    IgG
  • 应用备注

    WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

    别名

    HNRNPK

    背景

    Background: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.

    Aliases: Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK

    UniProt

    P61978
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