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Recombinant Filamin A 抗体

This anti-Filamin A antibody is a 兔 单克隆 antibody detecting Filamin A in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7127493
发货至: 中国

Quick Overview for Recombinant Filamin A 抗体 (ABIN7127493)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

抗体类型

Recombinant Antibody

适用

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宿主

  • 99
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克隆类型

  • 88
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单克隆

标记

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This Filamin A antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA

克隆位点

1B2
  • 交叉反应

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Filamin A

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    FLNA

    背景

    Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

    Aliases: Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin), FLNA, FLN FLN1

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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