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Recombinant CXCR4 抗体

CXCR4 适用: 人 ELISA, IF 宿主: 兔 Monoclonal 2F10 unconjugated Recombinant Antibody
产品编号 ABIN7127439
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗体类型
    Recombinant Antibody
    适用
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    宿主
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    克隆类型
    • 126
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    单克隆
    标记
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 109
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    ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity-chromatography
    免疫原
    A synthesized peptide derived from human CXCR4
    克隆位点
    2F10
    亚型
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Recommended dilution: IF:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CXCR4 (CXCR4 产品)
    背景

    Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

    Aliases: C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (FB22) (Fusin) (HM89) (LCR1) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Lipopolysaccharide-associated protein 3) (LAP-3) (LPS-associated protein 3) (NPYRL) (Stromal cell-derived factor 1 receptor) (SDF-1 receptor) (CD antigen CD184), CXCR4

    UniProt
    P61073
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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