CD151 抗体
Quick Overview for CD151 抗体 (ABIN7127232)
抗原
See all CD151 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- CD151 is involved in a wide variety of cell biological processes, including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein, which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including 1, 3, 4, i±2, i±3, i±5 and i±6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes, which are specialized junctional complexes that function as cell attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells, bone marrow stromal cells, C11 endothelial cells, HUVEC and several myeloid leukemia cell lines, however, no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu 149-Glu 213 of CD151 is the interface through which Integrin i±3/ 1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- The details of the immunogen for this antibody are not available.
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亚型
- IgG1
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anti-CD151 (CD151) (AA 101-200) antibody
CD151 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IHC (fro), IF (cc), IF (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) (N-Term) antibodyCD151 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) (AA 113-221) antibodyCD151 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) (AA 125-199) antibodyCD151 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) antibodyCD151 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) antibodyCD151 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD151 (CD151) antibodyCD151 适用: 人 WB, ELISA, FACS, IHC (p), IP, IHC (fro) 宿主: 小鼠 Monoclonal 11G5a unconjugated
anti-CD151 (CD151) antibodyCD151 适用: 人 WB 宿主: 兔 Polyclonal RB22792 unconjugated
anti-CD151 (CD151) (AA 1-253) antibodyCD151 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-CD151 (CD151) antibody (PE)CD151 适用: 人 FACS 宿主: 小鼠 Monoclonal 50-6 PE
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human tonsil or spleen. HT1080 cells.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- CD151
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别名
- CD151
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背景
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GP27, hemidesmosomal tetraspanin CD151, Membrane glycoprotein SFA-1, MER2, Platelet endothelial tetraspan antigen 3 (PETA3), platelet surface glycoprotein gp27, Platelet-endothelial cell tetraspan antigen 3, Platelet-endothelial tetraspan antigen 3, RAPH, Red blood cell antigen MER2, SFA1, Tetraspanin-24 (TSPAN24),CD151
Cellular localisation: Cell Surface -
分子量
- 28-32kDa
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基因ID
- 977, 654379
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UniProt
- P48509
抗原
-
