CD48 抗体 (AA 59-178)
Quick Overview for CD48 抗体 (AA 59-178) (ABIN7127217)
抗原
See all CD48 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 59-178
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特异性
 - Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
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交叉反应 (详细)
 - Human.
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纯化方法
 - 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
 - Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)
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亚型
 - IgG2
 
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应用备注
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Known_Application: Western Blot (2-4 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Raji cells. Human lymph node or tonsil.
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限制
 - 仅限研究用
 
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浓度
 - 1.0 mg/mL
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缓冲液
 - Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
 - Azide free
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
 - 24 months
 
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- CD48
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别名
 - CD48
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背景
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                        B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2,CD48 (Pan Leukocyte Marker)
Cellular localisation: Cell Surface - 
                                            
分子量
 - 45kDa
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基因ID
 - 962, 243564
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UniProt
 - P09326
 
抗原
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